D3 20000IU Capsule 10pcs

Uses

• Osteoporosis
• Hypoparathyroidism
• Rickets
• Osteomalacia
• Vitamin D Deficiency
• Pseudohypoparathyroidism
• Familial hypophosphatemia

Side Effects of

Rare symptoms include loss of appetite, fatigue, nausea, vomiting, diarrhea, constipation, weight loss, increased urination, sweating, headache, thirst, dizziness, and elevated levels of calcium and phosphate in plasma and urine.

Dosage & Administration

For Capsules:

Adults:

• Treatment of Vitamin D3 deficiency: 40,000 IU once weekly for 7 weeks. Maintenance therapy requires 1,400-2,000 IU/day, with levels of 25-hydroxyvitamin D checked 3-4 months after starting maintenance therapy.
• Prevention of deficiency: 20,000 IU every 4 weeks, with higher doses needed in certain cases.
• Adjunct to osteoporosis therapy: 20,000 IU once a month.

Children (12-18 years):

• Treatment of deficiency: 20,000 IU every 2 weeks for 6 weeks.
• Prevention: 20,000 IU every 6 weeks.

For Film-Coated Tablets:

• 1,000 IU (1-2 tablets) daily, or as directed by a physician. Take with food or within 1 hour after a meal.

For Oroflash or Chewable Tablets:

• 1,000 to 2,000 IU daily, as directed by a physician. Take with food or within 1 hour after a meal, and swallow after chewing.

For Syrup:

• At Risk of Deficiency:
  • 0-1 year: 400 IU/day (2 ml)

1 year: 600 IU/day (3 ml)

• For Deficient Patients:
  • 0-1 year: 2,000 IU/day (+50,000 IU/week) for 6 weeks
  • 1-18 years: 2,000 IU/day for 6 weeks.

Use in Special Populations

The safety and effectiveness of Vitamin D3 in children under 12 years have not been established.

Overdose Effects

Overdose can lead to hypervitaminosis D.

Interaction

Certain drugs can cause Vitamin D3 deficiency by interfering with its absorption and metabolism, including magnesium-containing antacids, digoxin, thiazide diuretics, cholestyramine, colestipol, phenytoin, phenobarbital, orlistat, and mineral oil. Corticosteroids like prednisolone may increase the need for Vitamin D3.

Contraindications

Vitamin D3 is contraindicated in all conditions associated with hypercalcemia and in individuals with hypersensitivity to Vitamin D3 or its excipients. It should not be used if there is evidence of Vitamin D3 toxicity.

Pregnancy & Lactation

Studies suggest that doses up to 4,000 IU are safe during pregnancy. The recommended daily intake for pregnant women is 400 IU, though higher doses may be required for those deficient in Vitamin D3. Pregnant women should follow medical advice tailored to their specific needs.

Vitamin D3 and its metabolites are excreted in breast milk, but overdosing in infants due to breastfeeding has not been observed. When prescribing additional Vitamin D3 to a breastfed child, the dose received by the mother should be considered.

Precautions & Warnings

Plasma calcium levels should be monitored in patients on high doses of Vitamin D3, especially in those with renal impairment, or during pregnancy and lactation. Individuals taking digoxin, thiazide diuretics, or those with liver or kidney disease, hyperparathyroidism, lymphoma, tuberculosis, or granulomatous disease should consult a healthcare provider before taking Vitamin D3.

Storage Conditions

Store below 30°C, protected from light and moisture. Keep out of reach of children.